Molecular Details
DICL_CP_0318358
- N-(furan-2-ylmethyl)-3-propyl-3H-imidazo[45-b]pyridin-2-amine
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0318358
PubChem CID
N/A (Not available)
Molecular Formula
C14H16N4O Molecular Weight
256.309 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
MNEAXTRYQSPQIC-UHFFFAOYSA-N
InChI
InChI=1S/C14H16N4O/c1-2-8-18-13-12(6-3-7-15-13)17-14(18)16-10-11-5-4-9-19-11/h3-7,9H,2,8,10H2,1H3,(H...
IUPAC Name
N-(furan-2-ylmethyl)-3-propyl-3H-imidazo[45-b]pyridin-2-amine
CAS Number
N/A (Not available)
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
35 37 0 0 0 0 0 0 0 0999 V2000
-1.6756 -3.3044 -0.1239 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.5274 -1.8568 0.3333 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.3176 -0.917...
Experimental Data
Activity Data
Target Ion Channel
Short transient receptor potential channel 5
Uniprot Accession Number
Function
Inhibitor
Species
Homo sapiens (Human)
IC50
IC50: 15500 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
−60 mV mV
Temperature
Not mention
Test Method
Patch-clamping
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
19
Rotatable Bonds
5
logP
3.0464
Complexity
73.8537
TPSA (Ų)
55.88
H-Bond Donors
1
H-Bond Acceptors
5
Ring Count
3